Columbia eMERGE repositories
Columbia eMERGE sequence repository currently has 3,059 WES or WGS sequences from residents from the Washington Heights Community in Northern Manhattan and the disease-focused studies on chronic kidney disease, pediatric cardiac genomics, congenital diaphragmatic hernias, obesity, type 2 diabetes, pulmonary arterial hypertension, breast cancer, and others.
CUMC Biobank includes approximately 20,000 samples from patients in our tumor bank, brain bank, and investigator initiated research studies including fetal structural anomalies, rare pediatric diseases, birth defects, neurodegenerative conditions including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, cardiac diseases, and renal diseases.
Individualized Medicine through Application of GENomics (IMAGene) study
The IMAGene study is a study within the eMERGE study at Columbia University. The IMAGene study is enrolling a targeted population of 500 adults who have been patients at New York Presbyterian Columbia with in the last 2 years. This study will examine two specific groups: adults of Ashkenazi Jewish or Hispanic ancestry, and there are differences to interpretting genetic for individuals in these communities. The Ashkenazi Jewish population is a genetically well-defined population which makes it well suited to pilot a genomic screening study. Much less is known about how to interpret the genome of Hispanic individuals, posing greater challenges of implementation of genomic medicine.
The IMAGene study will focus on testing methods to educate individuals about genomic screening, how individuals make the decision to have genomic screening and how they adapt and use their results to make health and life decisions.
[IMAGENE]
Genomic Decision Support
[DECISION SUPPORT TOOL]